Diosmin Powder

Diosmin Powder - Premium Vascular Health Ingredient 

Diosmin Powder is a semi-synthetic flavonoid glycoside produced from hesperidin found in orange peel, primarily orange Aurantium L. In the food and pharmaceutical industries, this venoactive drug has been shown to help chronic venous dysfunction and microcirculatory illnesses. The product fixes the problems with natural flavonoids not being bioavailable by breaking down particles to less than 2 micrometers in size. This makes them dissolve and be absorbed more quickly by the body. Pharmaceutical-grade diosmin is made by Kingherbs Limited. It is a fine, grayish-yellow, hygroscopic powder with controlled particle dispersion that is more than 90% pure. For our extraction process, we only use food-grade ethanol and make sure that the amount of leftover liquid is less than 50 ppm, which is what EP requires. For product launches that need to happen quickly, we get rid of supply chain bottlenecks by having ready stock and business delivery in 3–5 days.

Diosmin Powder COA

Each batch includes detailed HPLC chromatograms for full traceability.

Diosmin Powder Benefits

Clinically Proven Vascular Support

A 2023-2024 randomized controlled trial demonstrated that 570 mg daily supplementation resulted in 41.7% reduction in heavy legs and 45.2% reduction in tired legs after 56 days. Responder rates doubled versus placebo groups.

Enhanced Venous Tone

You get improved vein elasticity through norepinephrine stabilization. This mechanism directly strengthens venous wall constriction and reduces varicosity symptoms.

Superior Lymphatic Drainage

Your formulation benefits from increased lymphatic flow rates and decreased intralymphatic pressure. This dual action reduces lower limb edema more effectively than single-mechanism competitors.

Microcirculatory Protection

You'll see reduced capillary hyperpermeability and inflammatory mediator suppression. These effects prevent fluid extravasation at the cellular level.

Antioxidant & Hepatoprotective Potential

Preclinical data indicates protection against NAFLD and alcohol-induced liver injury through Nrf2 pathway activation and oxidative stress reduction.

Diosmin Powder Applications

Dietary Supplements

• Tablets & Capsules: Directly compressible at 450-600 mg per dose
• Softgels: Oil-suspension formulations for enhanced bioavailability
• Powder Blends: Combined with hesperidin or horse chestnut extract

Pharmaceutical Preparations

• Venoactive drugs for chronic venous insufficiency (CVI)
• Hemorrhoid treatment formulations
• Adjunct therapy for systemic sclerosis digital ulcers

Functional Foods

• Beverage fortification (requires solubilization with cyclodextrins)
• Protein bar matrices for active lifestyle products

Cosmetic Applications

• Anti-inflammatory serums targeting rosacea and spider veins
• Microcirculation-boosting creams for under-eye darkness

Kingherbs provides application lab support for stability testing and solubility optimization of Diosmin Powder across all matrices.

Certificates

• ISO9001 Quality Management System Certificate

• FSSC22000 Food Safety System Certificate

• HACCP System Certificate

• HALAL Certification

• KOF-K Certification

• FDA Registration

• Part of Hunan Botanical Extract Association (HNBEA)

FAQ

Q1: What is the product and where does it come from?

A: The natural flavonoid glycoside diosmin comes from citrus fruits, especially the peels of sweet oranges and tangerines. It has been used as a medicine for almost one hundred years and is chemically removed from hesperidin, which is another flavonoid that is normally found in large amounts in citrus fruits. An active ingredient in food products and drugs meant to support arterial health is often the powder.

Q: To support vein health, how does the product work in the body?

A: Multiple processes within diosmin work together to improve the function of veins and blood flow. Increasing venous tone by stopping the breakdown of norepinephrine makes veins tighter and more flexible. Furthermore, it enhances lymphatic drainage by raising lymphatic movement and lowering intralymphatic pressure, which reduces swelling. Microvascularly, diosmin protects capillaries by lowering inflammation and hyperpermeability, which stops fluid from leaking into nearby tissues.

Q: Is the product good at helping with signs like heavy, tired legs?

A: Indeed, scientific studies strongly support its effectiveness. In 2023 and 2024, a recent randomized, double-blind, placebo-controlled study was done on healthy people with leg pain and spider veins. After 56 days of supplements, the participants showed significant changes. A diosmin-based supplement (570 mg daily) reduced the feeling of heavy legs by 41.7% and tired legs by 45.2% compared to the placebo group.

Q: In addition to helping with leg pain, what other health benefits might Diosmin have?

A: Most well known for its venotonic benefits (helping with hemorrhoids and chronic venous insufficiency), new study shows it may have more uses. Significant anti-inflammatory and antioxidant qualities in our product may help keep organs from getting hurt. Potentially protecting the liver from NAFLD and alcohol-related damage by lowering oxidative stress and stopping inflammatory pathways, according to preclinical studies. Researchers are also looking into how it can help people with systemic sclerosis fix digital sores.

Packaging and Transportation

As standard, 25 kg per fiber drum comes in two food-safe PE bags.

Sample orders come in bags of 1 kg metal foil.

MOQ: Samples and sample sales of a few kg are welcome; the business MOQ is 25 kg.

International messenger (3-5 days), plane freight, and ocean shipping are all ways to deliver.

Keep in a cool, dry place out of the light; it will last for 24 months.

Our transportation team makes sure that all of our deliveries go smoothly around the world and come with all the necessary paperwork, such as COAs, MSDSs, and phytosanitary certificates.

Why Choose Us?

25+ Years of Making Great Products

Kingherbs has been making botanical extracts since 1996. They are fully vertically integrated, which means they get their raw materials and make their products themselves.

Quality Controlled at the Source

We work directly with citrus planting bases to manage the whole process, from choosing the seeds to when the fruit is picked. This keeps the amount of hesperidin constant so that the rates of diosmin conversion stay the same.

Technology for Clean Extraction

We only use clean water and food-grade ethanol in our methods. We don't use any dangerous solvents at all. You get goods that are very pure in color and dissolve quickly.

A partnership approach to technology

We don't just sell materials; we also help with preparation. Our lab creates unique mixes, tests for stability, and sells softgel pills that are ready to go to market.

Quick and adaptable service

Delivery in 3–5 work days is possible with ready stock. We can handle small test orders for research and development, and we can easily handle large orders for business with stable wait times.

One-Stop Shopping

We also offer drugs, vitamins, minerals, amino acids, and plant products. This makes it easier to buy things by bringing together all of your suppliers in one place.

Our Warehouse and Shipment

Our Teams & Exhibitions

Contact Us

Ready to elevate your vascular health formulations with Diosmin Powder? Reach out to our technical team at info@kingherbs.com for samples, COAs, and application support.